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Do exercise to keep fit

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Health is wealth

Do exercise to keep fit

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Health is wealth

Do exercise to keep fit

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Health is wealth

Do exercise to keep fit

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Health is wealth

Do exercise to keep fit

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Health is wealth

A Novel drug prevents amyloid plaques, a hallmark of Alzheimer's disease.

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  A Novel drug prevents amyloid plaques, a hallmark of Alzheimer's disease. Amyloid plaques are pathological hallmarks of Alzheimer's disease (AD) -- clumps of misfolded proteins that accumulate in the brain, disrupting and killing neurons and resulting in the progressive cognitive impairment characteristic of the widespread neurological disorder. In a new study, published March 2, 2021, in the Journal of Experimental Medicine (JEM), researchers at the University of California San Diego School of Medicine, Massachusetts General Hospital, and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques. In studies using rodents and monkeys, the researchers report the drug was safe and effective, paving the way for possible clinical trials in humans. "Alzheimer's disease is an extraordinarily complex and multi-faceted condition that has, so far, defied effective treatment, let alone pre